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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
surAPeptidyl-prolyl cis-trans isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (296 aa)    
Predicted Functional Partners:
LSL_0477
Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); COG0537 [FGR] Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
  
   0.737
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
  
  
 0.647
LSL_0479
Protein ecsB; COG4473 [U] Predicted ABC-type exoprotein transport system, permease component.
 
     0.635
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
   
  
 0.617
LSL_1679
Hypothetical protein with PPE repeats; COG5651 [N] PPE-repeat proteins.
   
 
 0.615
LSL_0478
ABC transporter, ATP-binding protein; COG1131 [V] ABC-type multidrug transport system, ATPase component.
       0.588
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.588
ppiB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.523
tig
Trigger factor, ppiase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.522
pepC
COG3579 [E] Aminopeptidase C; Belongs to the peptidase C1 family.
  
   
 0.516
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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