Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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surAPeptidyl-prolyl cis-trans isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (296 aa)    
Predicted Functional Partners:
LSL_0477
Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); COG0537 [FGR] Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.
  
   0.735
LSL_0479
Protein ecsB; COG4473 [U] Predicted ABC-type exoprotein transport system, permease component.
 
   
 0.607
ppiB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.599
LSL_1679
Hypothetical protein with PPE repeats; COG5651 [N] PPE-repeat proteins.
   
 
 0.594
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
  
  
 0.587
yidC-2
60 kDa inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
 
  
 0.572
degP
Endopeptidase; COG0265 [O] Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
 
  
 0.551
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.548
LSL_1300
Conserved hypothetical protein.
  
   
 0.516
tig
Trigger factor, ppiase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.515
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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