Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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LSL_0477Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); COG0537 [FGR] Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (142 aa)    
Predicted Functional Partners:
LSL_0478
ABC transporter, ATP-binding protein; COG1131 [V] ABC-type multidrug transport system, ATPase component.
 
  
 0.838
LSL_0479
Protein ecsB; COG4473 [U] Predicted ABC-type exoprotein transport system, permease component.
     
 0.813
sir2
SIR2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.774
LSL_0476
Hypothetical protein.
       0.773
surA
Peptidyl-prolyl cis-trans isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
  
   0.735
glmM-2
Phosphoglucomutase; COG1109 [G] Phosphomannomutase.
  
   0.660
glnA
COG0174 [E] Glutamine synthetase.
  
   0.647
trmB
tRNA (m(7)G46) methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.585
LSL_0480
Phosphotransferase enzyme family; COG0510 [M] Predicted choline kinase involved in LPS biosynthesis.
     
 0.571
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
 
     0.505
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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