Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
tmcALConserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (380 aa)    
Predicted Functional Partners:
LSL_0506
Conserved hypothetical protein; COG1399 [R] Predicted metal-binding, possibly nucleic acid-binding protein.
 
     0.770
LSL_0509
Methyltransferase; COG4122 [R] Predicted O-methyltransferase; Belongs to the methyltransferase superfamily.
 
     0.699
LSL_0503
Conserved hypothetical protein, HD domain; COG1713 [H] Predicted HD superfamily hydrolase involved in NAD metabolism.
 
  
 0.698
LSL_1728
Phosphoesterase, DHH family protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.664
dnaE
DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.578
rpmF
COG0333 [J] Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
       0.555
LSL_0500
GTP-binding protein; COG1160 [R] Predicted GTPases.
 
     0.522
LSL_0501
Conserved hypothetical protein; COG1534 [J] Predicted RNA-binding protein containing KH domain, possibly ribosomal protein.
 
     0.487
trmB
tRNA (m(7)G46) methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
     0.447
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
    0.440
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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