Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0506Conserved hypothetical protein; COG1399 [R] Predicted metal-binding, possibly nucleic acid-binding protein. (181 aa)    
Predicted Functional Partners:
rpmF
COG0333 [J] Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
  
 0.971
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
    0.852
rpsP
COG0228 [J] Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
    0.843
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
    0.830
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
  
    0.825
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.820
infC
Bacterial Protein Translation Initiation Factor 3 (IF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
  
    0.807
rplD
LSU ribosomal protein L1E; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
    0.805
rpsB
COG0052 [J] Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
    0.802
dnaB
COG3611 [L] Replication initiation/membrane attachment protein.
 
     0.796
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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