node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSL_0070 | lexA | LSL_0070 | LSL_0540 | COG2738 [R] Predicted Zn-dependent protease. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.617 |
LSL_0070 | rpoD | LSL_0070 | LSL_0909 | COG2738 [R] Predicted Zn-dependent protease. | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.700 |
LSL_0541 | LSL_0542 | LSL_0541 | LSL_0542 | COG0718 [S] Uncharacterized protein conserved in bacteria. | COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.792 |
LSL_0541 | lexA | LSL_0541 | LSL_0540 | COG0718 [S] Uncharacterized protein conserved in bacteria. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.794 |
LSL_0542 | LSL_0541 | LSL_0542 | LSL_0541 | COG0718 [S] Uncharacterized protein conserved in bacteria. | COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.792 |
LSL_0542 | lexA | LSL_0542 | LSL_0540 | COG0718 [S] Uncharacterized protein conserved in bacteria. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.633 |
dinG | dinP | LSL_0686 | LSL_1162 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.549 |
dinG | lexA | LSL_0686 | LSL_0540 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.638 |
dinG | polA | LSL_0686 | LSL_0488 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.898 |
dinG | recA | LSL_0686 | LSL_1130 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.629 |
dinG | recJ | LSL_0686 | LSL_1091 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | COG0608 [L] Single-stranded DNA-specific exonuclease. | 0.638 |
dinG | recN | LSL_0686 | LSL_0539 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.532 |
dinP | dinG | LSL_1162 | LSL_0686 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | 0.549 |
dinP | lexA | LSL_1162 | LSL_0540 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.788 |
dinP | polA | LSL_1162 | LSL_0488 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.803 |
dinP | recA | LSL_1162 | LSL_1130 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.816 |
dinP | recJ | LSL_1162 | LSL_1091 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | COG0608 [L] Single-stranded DNA-specific exonuclease. | 0.474 |
dinP | recN | LSL_1162 | LSL_0539 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA repair protein; May be involved in recombinational repair of damaged DNA. | 0.506 |
lexA | LSL_0070 | LSL_0540 | LSL_0070 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | COG2738 [R] Predicted Zn-dependent protease. | 0.617 |
lexA | LSL_0541 | LSL_0540 | LSL_0541 | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | COG0718 [S] Uncharacterized protein conserved in bacteria. | 0.794 |