Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LSL_0541COG0718 [S] Uncharacterized protein conserved in bacteria. (84 aa)    
Predicted Functional Partners:
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.771
LSL_0542
COG0718 [S] Uncharacterized protein conserved in bacteria.
 
    0.767
LSL_1108
COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.
  
  
 0.555
LSL_0570
Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.
  
   
 0.498
LSL_0553
Conserved hypothetical protein, rhodanese-like domain; COG0607 [P] Rhodanese-related sulfurtransferase.
 
     0.451
LSL_1078
Conserved hypothetical protein.
      
 0.439
LSL_0981
Oligosaccharide translocase; COG2244 [R] Membrane protein involved in the export of O-antigen and teichoic acid; flippase.
  
     0.434
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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