Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0544Hypothetical protein; COG1694 [R] Predicted pyrophosphatase. (99 aa)    
Predicted Functional Partners:
engB
GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
      0.948
mmsB
COG2084 [I] 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
      0.657
LSL_0545
Hypothetical membrane spanning protein.
       0.532
LSL_0542
COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.517
LSL_0546
Transposase ISLasa5a, IS3 family; COG0675 [L] Transposase and inactivated derivatives.
 
     0.481
LSL_0648
Hypothetical protein.
  
     0.456
LSL_0903
COG0718 [S] Uncharacterized protein conserved in bacteria.
  
     0.444
LSL_1089
COG0344 [S] Predicted membrane protein.
  
     0.439
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.437
pykF
COG0469 [G] Pyruvate kinase; Belongs to the pyruvate kinase family.
       0.422
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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