STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0549COG0212 [H] 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (182 aa)    
Predicted Functional Partners:
LSL_0550
Integral membrane protein, Rhomboid family; COG0705 [R] Uncharacterized membrane protein (homolog of Drosophila rhomboid).
  
    0.946
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.933
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.930
LSL_0551
COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.786
LSL_0552
Glucokinase; COG1940 [KG] Transcriptional regulator/sugar kinase.
       0.786
rpmG
COG0267 [J] Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
       0.779
LSL_0553
Conserved hypothetical protein, rhodanese-like domain; COG0607 [P] Rhodanese-related sulfurtransferase.
  
    0.734
pheT
COG0072 [J] Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.632
LSL_1088
COG0768 [M] Cell division protein FtsI/penicillin-binding protein 2.
  
    0.476
LSL_0547
Hypothetical protein; COG0419 [L] ATPase involved in DNA repair.
  
    0.464
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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