Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0553Conserved hypothetical protein, rhodanese-like domain; COG0607 [P] Rhodanese-related sulfurtransferase. (137 aa)    
Predicted Functional Partners:
LSL_0551
COG0718 [S] Uncharacterized protein conserved in bacteria.
 
     0.802
LSL_0552
Glucokinase; COG1940 [KG] Transcriptional regulator/sugar kinase.
       0.772
LSL_0550
Integral membrane protein, Rhomboid family; COG0705 [R] Uncharacterized membrane protein (homolog of Drosophila rhomboid).
  
  
 0.733
LSL_0549
COG0212 [H] 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.706
recU
Recombination protein; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.646
LSL_0432
COG0827 [L] Adenine-specific DNA methylase.
  
    0.642
rpmG
COG0267 [J] Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
  
    0.580
LSL_1088
COG0768 [M] Cell division protein FtsI/penicillin-binding protein 2.
 
     0.544
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.533
LSL_0542
COG0718 [S] Uncharacterized protein conserved in bacteria.
 
     0.523
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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