Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0556Aluminum resistance protein; COG4100 [P] Cystathionine beta-lyase family protein involved in aluminum resistance. (420 aa)    
Predicted Functional Partners:
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.815
fabG-2
3-oxoacyl-[acyl-carrier protein] reductase; COG1028 [IQR] Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
     0.751
ddlA
D-alanine--D-alanine ligase; Cell wall formation.
      0.723
glnR
Glutamine synthetase repressor; COG0640 [K] Predicted transcriptional regulators.
       0.629
glnA
COG0174 [E] Glutamine synthetase.
       0.579
LSL_0554
Conserved hypothetical protein.
       0.567
LSL_0168
COG0531 [E] Amino acid transporters.
  
     0.555
sepF
Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
 
     0.551
LSL_1000
Hypothetical membrane spanning protein.
  
     0.542
LSL_1110
COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.
 
     0.497
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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