infB protein (Lactobacillus salivarius) - STRING interaction network

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infB

Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (737 aa)

Predicted Functional Partners:

nusA

0.994

truB

0.994

rPL

0.993

rbfA

0.992

rpsB

0.981

LSL_0570

0.979

rpsD

0.974

rpsC

0.965

rpsE

0.959

rimP

0.955

Your Current Organism:

Lactobacillus salivarius

NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSL_0570	infB	LSL_0570	LSL_0572	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.979
LSL_0570	nusA	LSL_0570	LSL_0569	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	N utilization substance protein A; Participates in both transcription termination and antitermination.	0.993
LSL_0570	rPL	LSL_0570	LSL_0571	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	COG1358 [J] Ribosomal protein HS6-type (S12/L30/L7a).	0.996
LSL_0570	rbfA	LSL_0570	LSL_0573	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.	0.788
LSL_0570	rimP	LSL_0570	LSL_0568	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.	0.989
LSL_0570	rpsB	LSL_0570	LSL_0511	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	COG0052 [J] Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.478
LSL_0570	truB	LSL_0570	LSL_0574	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.735
infB	LSL_0570	LSL_0572	LSL_0570	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	0.979
infB	nusA	LSL_0572	LSL_0569	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	N utilization substance protein A; Participates in both transcription termination and antitermination.	0.994
infB	rPL	LSL_0572	LSL_0571	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	COG1358 [J] Ribosomal protein HS6-type (S12/L30/L7a).	0.993
infB	rbfA	LSL_0572	LSL_0573	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.	0.992
infB	rimP	LSL_0572	LSL_0568	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.	0.955
infB	rpsB	LSL_0572	LSL_0511	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	COG0052 [J] Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.981
infB	rpsC	LSL_0572	LSL_1429	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.	0.965
infB	rpsD	LSL_0572	LSL_1077	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.974
infB	rpsE	LSL_0572	LSL_1418	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.959
infB	truB	LSL_0572	LSL_0574	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.994
nusA	LSL_0570	LSL_0569	LSL_0570	N utilization substance protein A; Participates in both transcription termination and antitermination.	Conserved hypothetical protein; COG2740 [K] Predicted nucleic-acid-binding protein implicated in transcription termination.	0.993
nusA	infB	LSL_0569	LSL_0572	N utilization substance protein A; Participates in both transcription termination and antitermination.	Bacterial Protein Translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.994
nusA	rPL	LSL_0569	LSL_0571	N utilization substance protein A; Participates in both transcription termination and antitermination.	COG1358 [J] Ribosomal protein HS6-type (S12/L30/L7a).	0.992

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