Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mreBRod shape-determining protein; COG1077 [D] Actin-like ATPase involved in cell morphogenesis. (328 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
 
 
 0.939
ftsW
Rod shape determining protein; COG0772 [D] Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 0.935
LSL_0605
Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.923
LSL_1132
Transcriptional regulator; COG0718 [S] Uncharacterized protein conserved in bacteria.
 
 
 0.827
LSL_0606
Hypothetical protein.
       0.756
murA-2
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
  
 0.755
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.682
LSL_0602
Hypothetical membrane spanning protein.
       0.642
mreD
COG1792 [M] Cell shape-determining protein.
  
  
 0.625
LSL_1088
COG0768 [M] Cell division protein FtsI/penicillin-binding protein 2.
 
 
 
 0.570
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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