node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
apt | gmk | LSL_1090 | LSL_0611 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.942 |
apt | guaA-3 | LSL_1090 | LSL_1537 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.987 |
apt | guaC | LSL_1090 | LSL_1139 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.946 |
apt | hpt | LSL_1090 | LSL_1354 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | COG0634 [F] Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.947 |
apt | xpt | LSL_1090 | LSL_1309 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.929 |
gmk | apt | LSL_0611 | LSL_1090 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.942 |
gmk | guaA-3 | LSL_0611 | LSL_1537 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.964 |
gmk | guaC | LSL_0611 | LSL_1139 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.917 |
gmk | hpt | LSL_0611 | LSL_1354 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | COG0634 [F] Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.927 |
gmk | nrdA | LSL_0611 | LSL_1232 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.914 |
gmk | nrdB | LSL_0611 | LSL_1233 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | COG0208 [F] Ribonucleotide reductase, beta subunit. | 0.909 |
gmk | pykF | LSL_0611 | LSL_0867 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | COG0469 [G] Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.953 |
gmk | relA | LSL_0611 | LSL_0822 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.925 |
gmk | rpoZ | LSL_0611 | LSL_0612 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.979 |
gmk | xpt | LSL_0611 | LSL_1309 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.945 |
guaA-3 | apt | LSL_1537 | LSL_1090 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.987 |
guaA-3 | gmk | LSL_1537 | LSL_0611 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.964 |
guaA-3 | guaC | LSL_1537 | LSL_1139 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.999 |
guaA-3 | hpt | LSL_1537 | LSL_1354 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | COG0634 [F] Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.969 |
guaA-3 | nrdA | LSL_1537 | LSL_1232 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.607 |