STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comEACOG1555 [L] DNA uptake protein and related DNA-binding proteins. (229 aa)    
Predicted Functional Partners:
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
 
  
 0.943
comEB
ComE operon protein 2; COG2131 [F] Deoxycytidylate deaminase.
  
  
 0.922
LSL_0424
ComG operon protein 1; COG2804 [NU] Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
  
  
 0.884
LSL_1207
ComF operon protein 1; COG4098 [L] Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
   
  
 0.883
LSL_0425
ComG operon protein 2; COG1459 [NU] Type II secretory pathway, component PulF.
  
  
 0.882
LSL_0426
ComG operon protein 3.
   
  
 0.814
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
      0.801
lon
ATP-dependent protease La; COG3480 [T] Predicted secreted protein containing a PDZ domain.
     0.768
holA
COG1466 [L] DNA polymerase III, delta subunit.
     
 0.753
pilD
COG1989 [NOU] Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
   
  
 0.726
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.