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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0680ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). (753 aa)    
Predicted Functional Partners:
comEA
COG1555 [L] DNA uptake protein and related DNA-binding proteins.
 
  
 0.943
holA
COG1466 [L] DNA polymerase III, delta subunit.
 
   
 0.937
comEB
ComE operon protein 2; COG2131 [F] Deoxycytidylate deaminase.
 
    0.920
LSL_0425
ComG operon protein 2; COG1459 [NU] Type II secretory pathway, component PulF.
 
  
 0.858
LSL_0719
DNA processing protein; COG0758 [LU] Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
  
 0.852
comFC
ComF operon protein 3; COG1040 [R] Predicted amidophosphoribosyltransferases.
 
  
 0.819
LSL_0424
ComG operon protein 1; COG2804 [NU] Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
 
  
 0.810
pilD
COG1989 [NOU] Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
 
  
 0.797
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.794
ftsK
Cell division protein; COG1674 [D] DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.
 
  
 0.794
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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