Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
LSL_0680ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). (753 aa)    
Predicted Functional Partners:
comEB
ComE operon protein 2; COG2131 [F] Deoxycytidylate deaminase.
 
  
 0.961
comEA
COG1555 [L] DNA uptake protein and related DNA-binding proteins.
 
  
 0.943
holA
COG1466 [L] DNA polymerase III, delta subunit.
 
   
 0.927
LSL_0425
ComG operon protein 2; COG1459 [NU] Type II secretory pathway, component PulF.
 
  
 0.881
comFC
ComF operon protein 3; COG1040 [R] Predicted amidophosphoribosyltransferases.
 
  
 0.858
LSL_0719
DNA processing protein; COG0758 [LU] Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
  
 0.853
LSL_0424
ComG operon protein 1; COG2804 [NU] Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
 
  
 0.850
pilD
COG1989 [NOU] Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
 
  
 0.844
ftsK
Cell division protein; COG1674 [D] DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.
 
  
 0.826
LSL_0427
Hypothetical protein.
  
  
 0.812
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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