STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0684COG3407 [I] Mevalonate pyrophosphate decarboxylase. (322 aa)    
Predicted Functional Partners:
LSL_0683
COG1577 [I] Mevalonate kinase.
 
 0.999
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.997
eRG
COG1577 [I] Mevalonate kinase.
 
  
 0.993
LSL_0526
COG3425 [I] 3-hydroxy-3-methylglutaryl CoA synthase.
 
 
 0.962
ispA
Geranyltranstransferase; COG0142 [H] Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 0.953
LSL_0224
COG1257 [I] Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.916
lysS
COG1190 [J] Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
    0.711
dinG
ATP-dependent helicase, DinG family; 3'-5' exonuclease.
       0.659
LSL_0687
Hypothetical secreted protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.575
LSL_1028
Heptaprenyl diphosphate synthase; COG0142 [H] Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.558
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.