Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0727Tetratricopeptide repeat family protein; COG0457 [R] FOG: TPR repeat. (222 aa)    
Predicted Functional Partners:
recD
Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
   0.932
gpmB-2
Phosphoglycerate mutase; COG0406 [G] Fructose-2,6-bisphosphatase.
 
    0.875
LSL_0851
Tetratricopeptide repeat family protein; COG0457 [R] FOG: TPR repeat.
 
 
 
 0.721
LSL_1300
Conserved hypothetical protein.
  
     0.707
LSL_0225
IpaB/EvcA family protein.
  
     0.684
LSL_1019
N-acetylglucosaminyltransferase; COG1215 [M] Glycosyltransferases, probably involved in cell wall biogenesis.
  
 
 0.672
LSL_0648
Hypothetical protein.
  
     0.619
LSL_1622
Transcriptional regulator, Cro/CI family; COG0583 [K] Transcriptional regulator.
  
     0.611
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.609
LSL_0037
Hypothetical membrane spanning protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
  
     0.587
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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