Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
clpP-2COG0740 [OU] Protease subunit of ATP-dependent Clp proteases; Belongs to the peptidase S14 family. (249 aa)    
Predicted Functional Partners:
LSL_0784
Portal protein; COG4672 [S] Phage-related protein.
    0.969
LSL_0783
Terminase large subunit; COG4626 [R] Phage terminase-like protein, large subunit.
 
     0.940
clpX
ATP-dependent clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 0.935
LSL_0782
COG3728 [L] Phage terminase, small subunit.
 
    0.915
LSL_0786
Phage prohead protease.
  
    0.798
clpE
ATP-dependent clp protease ATP-binding subunit; COG0542 [O] ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.714
clpL
ATP-dependent clp protease ATP-binding subunit; COG0542 [O] ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.661
clpC
Negative regulator of genetic competence; COG0542 [O] ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.661
clpB
Chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.661
mcrA-2
COG1403 [V] Restriction endonuclease.
 
    0.657
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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