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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSL_0832Transcriptional regulators, LysR family; COG0583 [K] Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (318 aa)    
Predicted Functional Partners:
ppa
COG1227 [C] Inorganic pyrophosphatase/exopolyphosphatase.
       0.823
LSL_0674
Transcriptional regulators, LysR family; COG0583 [K] Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.563
ftsL
Cell division protein ftsL; Essential cell division protein; Belongs to the FtsL family.
  
     0.556
LSL_1456
Conserved hypothetical protein.
  
     0.524
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
     
 0.515
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.508
gyrA-2
Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
  
  
 0.480
gyrB-2
Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
     
 0.455
LSL_0037
Hypothetical membrane spanning protein; COG0718 [S] Uncharacterized protein conserved in bacteria.
  
     0.413
LSL_1314
Malolactic regulator, LysR family; COG0583 [K] Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.411
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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