Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0834Transcriptional regulator, DeoR family; COG1349 [KG] Transcriptional regulators of sugar metabolism. (250 aa)    
Predicted Functional Partners:
fruA
COG1299 [G] Phosphotransferase system, fructose-specific IIC component.
  
  
 0.890
fruK
1-phosphofructokinase; COG1105 [G] Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.686
araT-2
COG0436 [E] Aspartate/tyrosine/aromatic aminotransferase.
       0.592
LSL_1007
Conserved hypothetical protein.
  
    0.542
LSL_1315
Transcriptional regulator, MarR family; COG0583 [K] Transcriptional regulator.
  
     0.495
ppa
COG1227 [C] Inorganic pyrophosphatase/exopolyphosphatase.
       0.451
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.448
glpO
Alpha-glycerophosphate oxidase; COG0240 [C] Glycerol-3-phosphate dehydrogenase.
 
  
 0.412
LSL_1628
COG3711 [K] Transcriptional antiterminator.
  
  
 0.412
LSL_0832
Transcriptional regulators, LysR family; COG0583 [K] Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.409
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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