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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (325 aa)    
Predicted Functional Partners:
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
 
 0.988
dapH
Tetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
 
  
 0.961
LSL_0469
N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
 
  
 0.959
LSL_0133
COG0624 [E] Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
    
 0.936
LSL_1467
COG0624 [E] Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
    
 0.936
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
   
 0.910
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.903
carB
COG0458 [EF] Carbamoylphosphate synthase large subunit (split gene in MJ).
      0.882
nudF
ADP-ribose pyrophosphatase; COG0494 [LR] NTP pyrophosphohydrolases including oxidative damage repair enzymes.
   
 
 0.867
asd
COG0136 [E] Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
  
 0.787
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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