Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pykF
COG0469 [G] Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.998
pgi
COG0166 [G] Glucose-6-phosphate isomerase.
  
 0.985
fba
COG0191 [G] Fructose/tagatose bisphosphate aldolase.
 
 
 0.981
fruK
1-phosphofructokinase; COG1105 [G] Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.935
manA
COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.926
LSL_1461
Fructokinase; COG1940 [KG] Transcriptional regulator/sugar kinase.
    
 0.922
mtlD
COG0246 [G] Mannitol-1-phosphate/altronate dehydrogenases.
    
 0.918
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.886
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.863
pgk
COG0126 [G] 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 0.813
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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