Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
celBCellobiose PTS, EIIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. (449 aa)    
Predicted Functional Partners:
LSL_0913
Putative acyltransferases and hydrolases with the alpha/beta hydrolase fold; COG4814 [R] Uncharacterized protein with an alpha/beta hydrolase fold.
 
     0.965
ptsH
Phosphocarrier protein HPr; COG1925 [G] Phosphotransferase system, HPr-related proteins.
    
  0.905
fruA
COG1299 [G] Phosphotransferase system, fructose-specific IIC component.
 
  
 0.807
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.769
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
  
  
 0.763
LSL_1628
COG3711 [K] Transcriptional antiterminator.
 
  
 0.729
fruK
1-phosphofructokinase; COG1105 [G] Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
  
 0.635
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
  
  
 0.612
LSL_0362
COG2404 [R] Predicted phosphohydrolase (DHH superfamily).
  
     0.491
LSL_1619
PTS system, mannitol-specific IIA component; COG4668 [G] Mannitol/fructose-specific phosphotransferase system, IIA domain.
  
  
 0.459
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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