STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
hsdRType I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1004 aa)    
Predicted Functional Partners:
hsdM
COG0286 [V] Type I restriction-modification system methyltransferase subunit.
  
 0.997
hsdS-3
Type I restriction-modification system specificity subunit; COG0732 [V] Restriction endonuclease S subunits.
 
  
 0.986
hsdS-2
Type I restriction-modification system specificity subunit; COG0732 [V] Restriction endonuclease S subunits.
 
  
 0.934
hsdS
Type I restriction-modification system specificity subunit; COG0732 [V] Restriction endonuclease S subunits.
 
   
 0.819
LSL_0767
Hypothetical protein, phage associated; COG0286 [V] Type I restriction-modification system methyltransferase subunit.
  
  
 0.787
xerC-4
DNA integration/recombination/inversion protein; COG0582 [L] Integrase; Belongs to the 'phage' integrase family.
 
   
 0.780
ssl
DNA/RNA helicase, DEAD/DEAH box family; COG1061 [KL] DNA or RNA helicases of superfamily II.
  
  
 0.487
ssl-2
DNA/RNA helicase, DEAD/DEAH box family; COG1061 [KL] DNA or RNA helicases of superfamily II.
  
  
 0.487
LSL_0921
Hypothetical protein.
       0.469
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
     
 0.404
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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