Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_0930COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0398 family. (183 aa)    
Predicted Functional Partners:
LSL_0851
Tetratricopeptide repeat family protein; COG0457 [R] FOG: TPR repeat.
  
     0.664
LSL_0479
Protein ecsB; COG4473 [U] Predicted ABC-type exoprotein transport system, permease component.
  
     0.598
ftsQ
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
     0.560
adeC
COG1001 [F] Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.512
recU
Recombination protein; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
    0.512
LSL_0394
Sulfatase family protein; COG1368 [M] Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.
  
     0.499
divIVA
Cell division initiation protein DivIVA; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
     
 0.494
LSL_0432
COG0827 [L] Adenine-specific DNA methylase.
  
     0.492
LSL_0465
Sulfatase family protein; COG1368 [M] Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.
  
     0.455
LSL_0839
Conserved hypothetical protein; COG0116 [L] Predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.
 
    0.438
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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