Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cfaCOG2230 [M] Cyclopropane fatty acid synthase and related methyltransferases. (391 aa)    
Predicted Functional Partners:
LSL_1313
COG0281 [C] Malic enzyme.
      
 0.498
guaA-3
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.466
xerC-7
Integrase/recombinase, XerC/CodV family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
       0.449
LSL_0950
Transcription regulator; COG1597 [IR] Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
       0.431
hslV
ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
       0.410
LSL_1500
Conserved hypothetical protein; COG0628 [R] Predicted permease.
 
     0.409
metG
Methionyl-tRNA synthetase / Protein secretion chaperonin CsaA; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
       0.405
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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