Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LSL_1001Conserved hypothetical protein; COG1073 [R] Hydrolases of the alpha/beta superfamily. (257 aa)    
Predicted Functional Partners:
LSL_1000
Hypothetical membrane spanning protein.
 
     0.806
LSL_0999
Putative 23S rRNA m(5)C methyltransferase; COG0144 [J] tRNA and rRNA cytosine-C5-methylases.
       0.775
wecD-4
Acetyltransferase, GNAT family; COG0454 [KR] Histone acetyltransferase HPA2 and related acetyltransferases.
       0.722
LSL_1002
Hydrolase, HAD superfamily; COG0561 [R] Predicted hydrolases of the HAD superfamily.
       0.619
LSL_1213
Membrane-bound protease, CAAX family; COG1266 [R] Predicted metal-dependent membrane protease.
 
     0.535
LSL_1106
COG1286 [R] Uncharacterized membrane protein, required for colicin V production.
  
     0.507
LSL_0545
Hypothetical membrane spanning protein.
 
     0.498
scrA
PTS system, sucrose-specific IIABC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
    
   0.478
treB
PTS system, trehalose-specific IIBC component; COG1263 [G] Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
    
   0.478
LSL_0941
RibT protein.
 
     0.467
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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