Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_1008Transcriptional regulator, AraC family; COG2207 [K] AraC-type DNA-binding domain-containing proteins. (278 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.727
galA
COG3345 [G] Alpha-galactosidase.
 
     0.656
LSL_1007
Conserved hypothetical protein.
       0.566
LSL_1006
COG4690 [E] Dipeptidase.
       0.548
lacZ
COG3250 [G] Beta-galactosidase/beta-glucuronidase.
 
   
 0.531
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.529
fruA
COG1299 [G] Phosphotransferase system, fructose-specific IIC component.
   
 
 0.426
LSL_1628
COG3711 [K] Transcriptional antiterminator.
    
 
 0.405
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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