Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mutT7,8-dihydro-8-oxoguanine-triphosphatase; COG0494 [LR] NTP pyrophosphohydrolases including oxidative damage repair enzymes. (140 aa)    
Predicted Functional Partners:
ssl
DNA/RNA helicase, DEAD/DEAH box family; COG1061 [KL] DNA or RNA helicases of superfamily II.
 
    0.951
ssl-2
DNA/RNA helicase, DEAD/DEAH box family; COG1061 [KL] DNA or RNA helicases of superfamily II.
    0.771
wecD-6
Acetyltransferase, GNAT family; COG0454 [KR] Histone acetyltransferase HPA2 and related acetyltransferases.
  
    0.720
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.543
LSL_1009
Hypothetical membrane spanning protein.
       0.543
galA
COG3345 [G] Alpha-galactosidase.
       0.543
LSL_1011
Hypothetical protein.
       0.543
rnr
Ribonuclease R 1; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
 0.492
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
  
 
 0.466
LSL_1134
Peptidase, M16 family; COG0612 [R] Predicted Zn-dependent peptidases.
   
   0.450
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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