Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
minDCell division inhibitor; COG2894 [D] Septum formation inhibitor-activating ATPase. (267 aa)    
Predicted Functional Partners:
minC
Cell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
 
 
 0.999
mreC
Rod shape-determining protein; Involved in formation and maintenance of cell shape.
  
    0.949
mreD
COG1792 [M] Cell shape-determining protein.
  
  
 0.948
mreB-2
Rod shape-determining protein; COG1077 [D] Actin-like ATPase involved in cell morphogenesis.
  
 
 0.839
accA
COG0825 [I] Acetyl-CoA carboxylase alpha subunit.
 
    0.743
LSL_1183
Hypothetical membrane spanning protein; COG0265 [O] Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
     0.521
guaA-3
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.471
radC
COG2003 [L] DNA repair proteins; Belongs to the UPF0758 family.
  
    0.469
mreB
Rod shape-determining protein; COG1077 [D] Actin-like ATPase involved in cell morphogenesis.
  
 
 0.453
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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