node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSL_0680 | cgtA | LSL_0680 | LSL_1097 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.477 |
LSL_0680 | dinG | LSL_0680 | LSL_0686 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | 0.517 |
LSL_0680 | polA | LSL_0680 | LSL_0488 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.517 |
LSL_0680 | recJ | LSL_0680 | LSL_1091 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | COG0608 [L] Single-stranded DNA-specific exonuclease. | 0.793 |
LSL_0680 | ruvB | LSL_0680 | LSL_1125 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.696 |
LSL_0680 | uvrA | LSL_0680 | LSL_1174 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.434 |
LSL_0680 | uvrB | LSL_0680 | LSL_1175 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.558 |
LSL_0680 | uvrC | LSL_0680 | LSL_1098 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.684 |
cgtA | LSL_0680 | LSL_1097 | LSL_0680 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.477 |
cgtA | polA | LSL_1097 | LSL_0488 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.782 |
cgtA | recJ | LSL_1097 | LSL_1091 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | COG0608 [L] Single-stranded DNA-specific exonuclease. | 0.573 |
cgtA | uvrC | LSL_1097 | LSL_1098 | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.726 |
dinG | LSL_0680 | LSL_0686 | LSL_0680 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.517 |
dinG | mutL | LSL_0686 | LSL_1127 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.667 |
dinG | pcrA | LSL_0686 | LSL_1349 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | COG0210 [L] Superfamily I DNA and RNA helicases. | 0.715 |
dinG | polA | LSL_0686 | LSL_0488 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.898 |
dinG | recJ | LSL_0686 | LSL_1091 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | COG0608 [L] Single-stranded DNA-specific exonuclease. | 0.638 |
dinG | ruvB | LSL_0686 | LSL_1125 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.421 |
dinG | uvrA | LSL_0686 | LSL_1174 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.481 |
dinG | uvrB | LSL_0686 | LSL_1175 | ATP-dependent helicase, DinG family; 3'-5' exonuclease. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.454 |