STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutSDNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (786 aa)    
Predicted Functional Partners:
mutS-2
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.935
LSL_1106
COG1286 [R] Uncharacterized membrane protein, required for colicin V production.
     
 0.834
LSL_1107
Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
       0.825
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.817
LSL_0873
Fibronectin-binding protein / Fibrinogen-binding protein; COG1293 [K] Predicted RNA-binding protein homologous to eukaryotic snRNP.
 
   
 0.750
trxA-2
Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
       0.735
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.724
rpmI
COG0291 [J] Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.723
LSL_1110
COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.
 
     0.723
recJ
COG0608 [L] Single-stranded DNA-specific exonuclease.
 
   
 0.718
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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