LSL_1106 protein (Lactobacillus salivarius) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LSL_1106

COG1286 [R] Uncharacterized membrane protein, required for colicin V production. (164 aa)

Predicted Functional Partners:

LSL_1107

0.926

purF

0.901

mutS

0.834

purM

0.800

purC

0.781

LSL_1108

0.757

trxA-2

0.717

purE

0.712

LSL_1109

0.704

LSL_1110

0.698

Your Current Organism:

Lactobacillus salivarius

NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSL_1106	LSL_1107	LSL_1106	LSL_1107	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	0.926
LSL_1106	LSL_1108	LSL_1106	LSL_1108	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	0.757
LSL_1106	LSL_1109	LSL_1106	LSL_1109	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.	0.704
LSL_1106	LSL_1110	LSL_1106	LSL_1110	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.	0.698
LSL_1106	mutS	LSL_1106	LSL_1105	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.	0.834
LSL_1106	purC	LSL_1106	LSL_0663	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	COG0152 [F] Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.	0.781
LSL_1106	purE	LSL_1106	LSL_0515	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.712
LSL_1106	purF	LSL_1106	LSL_0667	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.901
LSL_1106	purM	LSL_1106	LSL_0668	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 [F] Phosphoribosylaminoimidazole (AIR) synthetase.	0.800
LSL_1106	trxA-2	LSL_1106	LSL_1104	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.	0.717
LSL_1107	LSL_1106	LSL_1107	LSL_1106	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	0.926
LSL_1107	LSL_1108	LSL_1107	LSL_1108	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	0.666
LSL_1107	LSL_1109	LSL_1107	LSL_1109	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	Endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.	0.627
LSL_1107	LSL_1110	LSL_1107	LSL_1110	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.	0.633
LSL_1107	mutS	LSL_1107	LSL_1105	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.	0.825
LSL_1107	trxA-2	LSL_1107	LSL_1104	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	Thioredoxin; COG0526 [OC] Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.	0.631
LSL_1108	LSL_1106	LSL_1108	LSL_1106	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	COG1286 [R] Uncharacterized membrane protein, required for colicin V production.	0.757
LSL_1108	LSL_1107	LSL_1108	LSL_1107	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.	0.666
LSL_1108	LSL_1109	LSL_1108	LSL_1109	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	Endonuclease involved in recombination; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.	0.886
LSL_1108	LSL_1110	LSL_1108	LSL_1110	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0473 family.	COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.	0.859

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About