Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ftsKCell division protein; COG1674 [D] DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family. (759 aa)    
Predicted Functional Partners:
mbp2
Mucus binding protein; COG3652 [S] Predicted outer membrane protein.
  
 
 0.874
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.844
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
 
  
 0.826
ftsQ
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
 
 0.803
LSL_1136
23S rRNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.787
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.752
parB
Chromosome partitioning protein, DNA-binding protein; COG0640 [K] Predicted transcriptional regulators; Belongs to the ParB family.
  
  
 0.746
LSL_1079
ATPase, AAA family; COG2256 [L] ATPase related to the helicase subunit of the Holliday junction resolvase.
  
 0.715
parB-2
Chromosome partitioning protein; COG0640 [K] Predicted transcriptional regulators; Belongs to the ParB family.
  
  
 0.705
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.686
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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