Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_1183Hypothetical membrane spanning protein; COG0265 [O] Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. (375 aa)    
Predicted Functional Partners:
LSL_1180
COG0583 [K] Transcriptional regulator.
  
  
 0.828
baeS-4
Two component system histidine kinase; COG0642 [T] Signal transduction histidine kinase.
  
  
 0.800
LSL_1182
Alkaline phosphatase synthesis two-component response regulator phoP; COG0745 [TK] Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.798
minC
Cell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
  
   
 0.790
LSL_1179
COG0344 [S] Predicted membrane protein.
       0.745
LSL_1244
Conserved hypothetical protein; COG3688 [R] Predicted RNA-binding protein containing a PIN domain.
  
     0.717
LSL_1485
Conserved hypothetical protein.
  
   
 0.701
LSL_1103
Conserved hypothetical protein.
  
     0.647
LSL_1225
Conserved hypothetical protein.
 
     0.625
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.606
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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