Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
comFCComF operon protein 3; COG1040 [R] Predicted amidophosphoribosyltransferases. (228 aa)    
Predicted Functional Partners:
LSL_1207
ComF operon protein 1; COG4098 [L] Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
 
  
 0.976
LSL_0680
ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily).
 
  
 0.858
LSL_0719
DNA processing protein; COG0758 [LU] Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
 
 
 0.854
LSL_0425
ComG operon protein 2; COG1459 [NU] Type II secretory pathway, component PulF.
 
  
 0.643
comEA
COG1555 [L] DNA uptake protein and related DNA-binding proteins.
  
  
 0.633
nagA
COG1820 [G] N-acetylglucosamine-6-phosphate deacetylase.
  
    0.602
comEB
ComE operon protein 2; COG2131 [F] Deoxycytidylate deaminase.
  
  
 0.592
LSL_0424
ComG operon protein 1; COG2804 [NU] Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.
  
  
 0.581
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
  
 0.570
LSL_1208
Undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase; COG0472 [M] UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.
       0.559
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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