Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_1258Metallopeptidase, SprT family; COG0718 [S] Uncharacterized protein conserved in bacteria; Belongs to the SprT family. (145 aa)    
Predicted Functional Partners:
LSL_1259
COG2183 [K] Transcriptional accessory protein; contains S1 RNA binding domain.
  
  
 0.880
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.736
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.632
LSL_0479
Protein ecsB; COG4473 [U] Predicted ABC-type exoprotein transport system, permease component.
  
     0.612
lon
ATP-dependent protease La; COG3480 [T] Predicted secreted protein containing a PDZ domain.
 
     0.584
LSL_0659
COG0718 [S] Uncharacterized protein conserved in bacteria.
 
     0.483
fabH-2
COG0332 [I] 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. FabH family.
       0.434
LSL_0500
GTP-binding protein; COG1160 [R] Predicted GTPases.
  
     0.424
LSL_1262
N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
       0.415
LSL_1222
Initiation-control protein; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.404
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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