Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mgtEMg2+ transporter; Acts as a magnesium transporter. (455 aa)    
Predicted Functional Partners:
nadK
ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.831
rluD-2
Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
       0.802
LSL_1305
GTP pyrophosphokinase; COG0718 [S] Uncharacterized protein conserved in bacteria.
       0.787
napA
Na+/H+ antiporter; COG0475 [P] Kef-type K+ transport systems, membrane components.
     
 0.602
topB
DNA topoisomerase III; COG0550 [L] Topoisomerase IA.
     
 0.510
LSL_1301
Transposase ISLasa4n, ISL3 family; COG0675 [L] Transposase and inactivated derivatives.
       0.453
dacA
Hypothetical membrane spanning protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
     
 0.450
guaA-3
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.427
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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