Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
LSL_1499Aminotransferase; COG1168 [E] Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (395 aa)    
Predicted Functional Partners:
metC
COG0626 [E] Cystathionine beta-lyases/cystathionine gamma-synthases.
 
 
 0.953
LSL_0204
Aminotransferase class I and II; COG1168 [E] Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
  
  
 
0.918
cysK
COG0031 [E] Cysteine synthase.
    
 0.911
cysK-2
COG0031 [E] Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.911
luxS
Autoinducer-2 production protein / Ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.900
MmuM
COG2040 [E] Homocysteine/selenocysteine methylase (S-methylmethionine-dependent).
     
  0.900
LSL_0613
Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
    
  0.801
thrA
COG0460 [E] Homoserine dehydrogenase.
    
  0.801
gshA
Glutamate--cysteine ligase; COG2918 [H] Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family.
     
  0.800
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
  0.800
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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