Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_1576COG0011 [S] Uncharacterized conserved protein. (214 aa)    
Predicted Functional Partners:
LSL_1577
Hydrolase, HAD superfamily; COG0637 [R] Predicted phosphatase/phosphohexomutase.
       0.741
hpf
Ribosome-associated factor Y; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
     
 0.539
LSL_1578
Multidrug resistance protein B; COG0477 [GEPR] Permeases of the major facilitator superfamily.
       0.522
LSL_0846
Conserved hypothetical protein; COG2384 [R] Predicted SAM-dependent methyltransferase.
   
    0.481
LSL_1207
ComF operon protein 1; COG4098 [L] Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
     
 0.457
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.439
corA
Magnesium and cobalt transport protein corA; COG0598 [P] Mg2+ and Co2+ transporters.
  
    0.434
comFC
ComF operon protein 3; COG1040 [R] Predicted amidophosphoribosyltransferases.
       0.415
LSL_0999
Putative 23S rRNA m(5)C methyltransferase; COG0144 [J] tRNA and rRNA cytosine-C5-methylases.
   
  
 0.408
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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