Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSL_1587ABC transporter substrate binding protein; COG0803 [P] ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family. (288 aa)    
Predicted Functional Partners:
LSL_1585
COG1108 [P] ABC-type Mn2+/Zn2+ transport systems, permease components.
 
  
 0.996
LSL_1586
ABC transporter, ATP-binding protein; COG1121 [P] ABC-type Mn/Zn transport systems, ATPase component.
 
  
 0.992
rpsN
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.744
LSL_0873
Fibronectin-binding protein / Fibrinogen-binding protein; COG1293 [K] Predicted RNA-binding protein homologous to eukaryotic snRNP.
      
 0.609
rpmB
COG0227 [J] Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.573
LSL_1584
Hypothetical membrane spanning protein.
   
   0.462
troR
Iron-dependent repressor; COG1321 [K] Mn-dependent transcriptional regulator.
  
  
 0.455
birA
Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
       0.439
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.439
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.430
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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