STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcrB(S)-3-O-geranylgeranylglyceryl phosphate synthase 1; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (239 aa)    
Predicted Functional Partners:
ubiA2
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
    
 0.964
gldA
Glycerol-1-phosphate dehydrogenase (NAD(P)); Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family.
     
 0.950
HQ_1711A
DUF1405 family protein; Product: IS1341-type transposase (nonfunctional); gene truncated at the N- and C-terminus.
  
     0.732
HQ_3324A
DUF1405 family protein.
  
     0.701
hemQ
Heme-binding protein HemQ; In the N-terminal section; belongs to the UPF0447 family.
  
     0.639
yvoF
O-acetyltransferase (homolog to galactoside O-acetyltransferase).
 
   
 0.464
HQ_1062A
Uncharacterized protein.
  
     0.463
sepF
Probable SepF protein.
  
     0.408
topA2
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.405
Your Current Organism:
Haloquadratum walsbyi DSM 16790
NCBI taxonomy Id: 362976
Other names: H. walsbyi DSM 16790, Haloquadratum walsbyi str. DSM 16790, Haloquadratum walsbyi strain DSM 16790
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.