| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hda1 | hstA | HQ_1437A | HQ_1436A | HdaI-type histone deacetylase. | Archaeal histone. | 0.978 |
| hda1 | rpa2 | HQ_1437A | HQ_1435A | HdaI-type histone deacetylase. | Replication protein A; Gene truncated at the N-terminus; product: IS1341-type transposase (nonfunctional). | 0.892 |
| hef | mcm | HQ_1020A | HQ_3662A | ATP-dependent RNA helicase/nuclease Hef. | ATP-dependent DNA helicase MCM (intein-containing). | 0.468 |
| hef | pcn | HQ_1020A | HQ_3686A | ATP-dependent RNA helicase/nuclease Hef. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.849 |
| hef | radA | HQ_1020A | HQ_3429A | ATP-dependent RNA helicase/nuclease Hef. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.726 |
| hef | rpa2 | HQ_1020A | HQ_1435A | ATP-dependent RNA helicase/nuclease Hef. | Replication protein A; Gene truncated at the N-terminus; product: IS1341-type transposase (nonfunctional). | 0.830 |
| hstA | hda1 | HQ_1436A | HQ_1437A | Archaeal histone. | HdaI-type histone deacetylase. | 0.978 |
| hstA | rpa2 | HQ_1436A | HQ_1435A | Archaeal histone. | Replication protein A; Gene truncated at the N-terminus; product: IS1341-type transposase (nonfunctional). | 0.948 |
| hstA | tfeA | HQ_1436A | HQ_2491A | Archaeal histone. | Transcription initiation factor TFE; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comp [...] | 0.508 |
| mcm | hef | HQ_3662A | HQ_1020A | ATP-dependent DNA helicase MCM (intein-containing). | ATP-dependent RNA helicase/nuclease Hef. | 0.468 |
| mcm | pcn | HQ_3662A | HQ_3686A | ATP-dependent DNA helicase MCM (intein-containing). | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.953 |
| mcm | radA | HQ_3662A | HQ_3429A | ATP-dependent DNA helicase MCM (intein-containing). | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.565 |
| mcm | rpa2 | HQ_3662A | HQ_1435A | ATP-dependent DNA helicase MCM (intein-containing). | Replication protein A; Gene truncated at the N-terminus; product: IS1341-type transposase (nonfunctional). | 0.832 |
| mcm | rpap1 | HQ_3662A | HQ_2404A | ATP-dependent DNA helicase MCM (intein-containing). | Rpa-associated protein. | 0.459 |
| mre11 | pcn | HQ_1700A | HQ_3686A | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.558 |
| mre11 | radA | HQ_1700A | HQ_3429A | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.880 |
| mre11 | rpa2 | HQ_1700A | HQ_1435A | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | Replication protein A; Gene truncated at the N-terminus; product: IS1341-type transposase (nonfunctional). | 0.723 |
| pcn | hef | HQ_3686A | HQ_1020A | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | ATP-dependent RNA helicase/nuclease Hef. | 0.849 |
| pcn | mcm | HQ_3686A | HQ_3662A | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | ATP-dependent DNA helicase MCM (intein-containing). | 0.953 |
| pcn | mre11 | HQ_3686A | HQ_1700A | DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | DNA double-strand break repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | 0.558 |
