STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrB2Peptide methionine sulfoxide reductase MsrB (R-form specific). (153 aa)    
Predicted Functional Partners:
msrA1
Peptide methionine sulfoxide reductase MsrA (S-form specific); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.960
msrA3
Peptide methionine sulfoxide reductase MsrA (S-form specific).
 
 0.807
msrA2
Peptide methionine sulfoxide reductase MsrA (S-form specific); Locus_tag: HQ_1927A; product: IS1341-type transposase (nonfunctional); gene is interrupted (frameshift,in-frame stop) and has been targetted by a mobile genetic element.
 
 
 0.699
sdhC
Succinate dehydrogenase subunit C.
  
  
 0.490
HQ_2919A
Pyridoxal phosphate-dependent aminotransferase.
       0.488
sdhD
Succinate dehydrogenase subunit D.
  
    0.481
grpE
DnaJ/DnaK ATPase stimulator GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...]
   
 
 0.422
Your Current Organism:
Haloquadratum walsbyi DSM 16790
NCBI taxonomy Id: 362976
Other names: H. walsbyi DSM 16790, Haloquadratum walsbyi str. DSM 16790, Haloquadratum walsbyi strain DSM 16790
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