STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (455 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase.
  
 0.989
guaA
GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP.
   
  
 0.973
fba
Fructose/tagatose bisphosphate aldolase.
  
 
 0.949
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.941
fbp
Fructose-1,6-bisphosphatase.
    
 0.939
glpX
Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins.
   
 
 0.934
xanB
Phosphomannose isomerase/GDP-mannose pyrophosphorylase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.929
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.916
eno
Enolase (2-phosphoglycerate dehydratase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.895
glgP
Carbohydrate phosphorylase family protein.
  
 
 0.841
Your Current Organism:
Lawsonia intracellularis
NCBI taxonomy Id: 363253
Other names: L. intracellularis PHE/MN1-00, Lawsonia intracellularis PHE/MN1-00, Lawsonia intracellularis str. PHE/MN1-00, Lawsonia intracellularis strain PHE/MN1-00
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.