STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF3D7_0525200Structural maintenance of chromosomes protein 6, putative. (1849 aa)    
Predicted Functional Partners:
PF3D7_1123800
Structural maintenance of chromosomes protein 5, putative.
   
 
 0.996
PF3D7_1368300
Uncharacterized protein.
    
 
 0.995
PF3D7_1451300
E3 SUMO-protein ligase NSE2, putative.
    
 
 0.995
PF3D7_0308100
Zinc finger protein, putative.
   
 
 0.886
PF3D7_1222400
AP2 domain transcription factor.
   
 
 0.886
PF3D7_0105900
3'-5' exonuclease, putative.
  
 
 0.833
PF3D7_1456500
SCD domain-containing protein.
   
 
 0.824
PF3D7_1304000
Condensin complex subunit 2, putative.
   
 
 0.814
PF3D7_1449400
Crossover junction endonuclease MUS81, putative.
    
 
 0.802
PFD0685c
Structural maintenance of chromosomes protein 3 homolog; Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity); Belongs to the SMC fami [...]
   
 
 0.800
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.