STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF3D7_0520500Phosphomethylpyrimidine kinase, putative. (310 aa)    
Predicted Functional Partners:
PF3D7_0616000
Pyridoxal kinase.
   
 
 0.794
PF3D7_0413700
Lysine decarboxylase-like protein, putative.
  
 
 0.770
PF3D7_0924300
Thiamine pyrophosphokinase.
  
  
 0.707
PF3D7_0520600
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
  
 
 0.689
PF3D7_1308900
mRNA-decapping enzyme 2, putative.
  
 
 0.689
PF3D7_0614000
Thiamine-phosphate synthase, putative.
  
 
 0.668
PF3D7_1251200
Coronin; Belongs to the WD repeat coronin family.
   
  
 0.635
PF3D7_1437200
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.628
PF3D7_1363700
Protein AMR1.
     
 0.594
pdx1
Pyridoxal 5'-phosphate synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by Pdx2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
     
 0.588
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.