PFE0570w protein (Plasmodium falciparum) - STRING interaction network

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Score

PFE0570w

MATH and LRR domain-containing protein PFE0570w. (10061 aa)

Predicted Functional Partners:

PF3D7_0915100

0.980

PF3D7_0629800

0.896

PF3D7_0811000

0.893

PF14_0175

0.793

PF3D7_1247500

0.629

SETVS

0.590

PF3D7_0509400

0.546

PF3D7_1411300

0.527

PF3D7_0705600

0.506

PF3D7_1455100

0.496

Your Current Organism:

Plasmodium falciparum

NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PF14_0175	PF3D7_0705600	Q8ILR9	C0H4K7	Protein PF14_0175.	RNA helicase, putative.	0.477
PF14_0175	PF3D7_0915100	Q8ILR9	Q8I301	Protein PF14_0175.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.571
PF14_0175	PFE0570w	Q8ILR9	Q8I3Z1	Protein PF14_0175.	MATH and LRR domain-containing protein PFE0570w.	0.793
PF14_0175	SETVS	Q8ILR9	Q8IE95	Protein PF14_0175.	Variant-silencing SET domain-containing protein; Histone methyltransferase that specifically represses expression of the surface antigen-coding var genes by mediating trimethylation of 'Lys-36' of histone H3 (H3K36me3) on var genes. SETVS-dependent H3K36me3 is specifically involved in var genes silencing, a central step malaria pathogenesis: each parasite contains 60 distinct var genes that each code for a different PfEMP1 protein. During infection, the clonal parasite population expresses only 1 gene at a time, while the 59 other var genes are silenced. The parasite then switches to t [...]	0.579
PF3D7_0509400	PF3D7_0705600	Q8I410	C0H4K7	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA helicase, putative.	0.756
PF3D7_0509400	PFE0570w	Q8I410	Q8I3Z1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	MATH and LRR domain-containing protein PFE0570w.	0.546
PF3D7_0509400	SETVS	Q8I410	Q8IE95	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Variant-silencing SET domain-containing protein; Histone methyltransferase that specifically represses expression of the surface antigen-coding var genes by mediating trimethylation of 'Lys-36' of histone H3 (H3K36me3) on var genes. SETVS-dependent H3K36me3 is specifically involved in var genes silencing, a central step malaria pathogenesis: each parasite contains 60 distinct var genes that each code for a different PfEMP1 protein. During infection, the clonal parasite population expresses only 1 gene at a time, while the 59 other var genes are silenced. The parasite then switches to t [...]	0.692
PF3D7_0629800	PF3D7_0811000	C6KTD3	Q8IAU5	Cullin-like protein, putative; Belongs to the cullin family.	Cullin-1, putative; Belongs to the cullin family.	0.400
PF3D7_0629800	PF3D7_0915100	C6KTD3	Q8I301	Cullin-like protein, putative; Belongs to the cullin family.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.580
PF3D7_0629800	PFE0570w	C6KTD3	Q8I3Z1	Cullin-like protein, putative; Belongs to the cullin family.	MATH and LRR domain-containing protein PFE0570w.	0.896
PF3D7_0705600	PF14_0175	C0H4K7	Q8ILR9	RNA helicase, putative.	Protein PF14_0175.	0.477
PF3D7_0705600	PF3D7_0509400	C0H4K7	Q8I410	RNA helicase, putative.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.756
PF3D7_0705600	PFE0570w	C0H4K7	Q8I3Z1	RNA helicase, putative.	MATH and LRR domain-containing protein PFE0570w.	0.506
PF3D7_0705600	SETVS	C0H4K7	Q8IE95	RNA helicase, putative.	Variant-silencing SET domain-containing protein; Histone methyltransferase that specifically represses expression of the surface antigen-coding var genes by mediating trimethylation of 'Lys-36' of histone H3 (H3K36me3) on var genes. SETVS-dependent H3K36me3 is specifically involved in var genes silencing, a central step malaria pathogenesis: each parasite contains 60 distinct var genes that each code for a different PfEMP1 protein. During infection, the clonal parasite population expresses only 1 gene at a time, while the 59 other var genes are silenced. The parasite then switches to t [...]	0.719
PF3D7_0811000	PF3D7_0629800	Q8IAU5	C6KTD3	Cullin-1, putative; Belongs to the cullin family.	Cullin-like protein, putative; Belongs to the cullin family.	0.400
PF3D7_0811000	PF3D7_0915100	Q8IAU5	Q8I301	Cullin-1, putative; Belongs to the cullin family.	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	0.580
PF3D7_0811000	PFE0570w	Q8IAU5	Q8I3Z1	Cullin-1, putative; Belongs to the cullin family.	MATH and LRR domain-containing protein PFE0570w.	0.893
PF3D7_0915100	PF14_0175	Q8I301	Q8ILR9	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	Protein PF14_0175.	0.571
PF3D7_0915100	PF3D7_0629800	Q8I301	C6KTD3	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	Cullin-like protein, putative; Belongs to the cullin family.	0.580
PF3D7_0915100	PF3D7_0811000	Q8I301	Q8IAU5	SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family.	Cullin-1, putative; Belongs to the cullin family.	0.580