STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PF11_0174Probable cathepsin C; Thiol protease. Has a role as a digestive enzyme. (700 aa)    
Predicted Functional Partners:
PF3D7_1247200
Uncharacterized protein.
    
   0.836
PF3D7_1360800
Falcilysin.
   
  
 0.806
PF3D7_0902800
Serine repeat antigen 9; Belongs to the peptidase C1 family.
      
 0.720
PF3D7_1311800
M1-family alanyl aminopeptidase.
   
  
 0.621
PF14_0076
Plasmepsin-1; Participates in the digestion of the host hemoglobin. Initial cleavage at the hinge region of hemoglobin, than cleaves at other sites, leading to denaturation of the molecule and to further degradation (By similarity); Belongs to the peptidase A1 family.
   
 
 0.575
PF3D7_1446200
M17 leucyl aminopeptidase.
   
  
 0.557
PF3D7_1454400
Aminopeptidase P; Belongs to the peptidase M24B family.
  
  
 0.522
PF3D7_1408000
Plasmepsin II; Belongs to the peptidase A1 family.
   
 
 0.512
PF3D7_1465700
Plasmepsin VIII, putative; Belongs to the peptidase A1 family.
   
 
 0.473
PF3D7_1347200
Nucleoside transporter 1.
   
  
 0.472
Your Current Organism:
Plasmodium falciparum
NCBI taxonomy Id: 36329
Other names: P. falciparum 3D7, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum 3D7
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