Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MPK4Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)    
Predicted Functional Partners:
LOC107914401
Protein MKS1-like.
    
 0.942
LOC107942699
Protein MKS1-like.
    
 0.942
LOC107940936
Nuclear speckle RNA-binding protein B-like.
    
 0.920
LOC107940146
Mitogen-activated protein kinase kinase 6-like isoform X1.
  
 
0.908
LOC107932209
Mitogen-activated protein kinase kinase 6-like isoform X1.
  
 
0.907
LOC107893314
Mitogen-activated protein kinase kinase 6-like; Belongs to the protein kinase superfamily.
  
 
0.905
MKK6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
 
0.905
LOC107907123
Mitogen-activated protein kinase kinase 2-like; Belongs to the protein kinase superfamily.
  
 
0.901
LOC107937701
Mitogen-activated protein kinase kinase 2-like; Belongs to the protein kinase superfamily.
  
 
0.901
LOC107901094
Mitogen-activated protein kinase kinase 2-like isoform X1; Belongs to the protein kinase superfamily.
  
 
0.900
Your Current Organism:
Gossypium hirsutum
NCBI taxonomy Id: 3635
Other names: American cotton, American upland cotton, G. hirsutum, Gossypium hirsutum L., Gossypium hirsutum subsp. mexicanum, Gossypium hirsutum subsp. mexicanum (Tod.) Mauer, Gossypium lanceolatum, Gossypium lanceolatum Tod., Gossypium purpurascens, Gossypium purpurascens Poir., cotton
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